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SMALL WORLD PUPPIES - Taurunum Angels Kennel
  • Home
  • Live Puppy Cameras
  • Puppy Deposits
  • Final Payment Options
  • Order Food & Heath Supplement
  • neuter / spay 2020 research
  • Puppy Go Home Check List
  • Available Female Cavalier Puppies
  • Available Baby Male Cavalier Puppies
  • Advanced Trained Male Cavalier Puppies
  • Financing
  • About Cavaliers
  • Cavalier King Charles Spaniel Parents
  • Our Veterinarians
  • AKC Certifications
  • Dry Eye Curly Coat Syndrome
  • Degenerative Myelopathy (DM)
  • Congenital Macrothrombocytopenia
  • Muscular Dystrophy
  • Episodic Falling Syndrome
  • Eye Certification
  • Patella Certification
  • Cardiac Evaluation (Heart)
  • CONTACT
  • LCPD Certification
  • Canine Hip Dysplasia
  • About Us
  • Puppy Culture
  • BrilliantPad Potty System
  • Help! My Puppy Wont Eat!
  • Dog Training
  • Training
SMALL WORLD PUPPIES - Taurunum Angels Kennel

DEGENERATIVE MYELOPATHY

OFA (Orthopedic Foundation for Animals)
Here is the latest finding about DM by the OFA 


https://www.ofa.org/diseases/dna-tested-diseases/dm

OFA Breed Statistics of DM by OFA research


Breed Testing Statement from OFA

Although any dog can be tested for Degenerative Myelopathy, it is possible that the genetic background that predominates in some breeds prevents the development of symptoms even in dogs testing affected (at risk). At this time we (OFA) are reluctant to recommend testing for members of breeds where the University of Missouri has not yet proven susceptibility to DM through microscopic examination of spinal cords from deceased dogs that exhibited symptoms of the disease. The required evidence of association between the genetic mutation and actual spinal cord evaluations has only been proven in the breeds listed:
  • American Eskimo Dogs
  • Bernese Mountain Dog
  • Borzoi
  • Boxers
  • Cardigan Welsh Corgi
  • Chesapeake Bay Retrievers
  • German Shepherd Dog
  • Golden Retriever
  • Great Pyrenees
  • Kerry Blue Terriers
  • Pembroke Welsh Corgis
  • Poodle
  • Pug
  • Rhodesian Ridgeback
  • Shetland Sheepdog
  • Soft Coated Wheaten Terriers
  • Wire Fox Terrier

What is DM? The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.
​
What does the result mean if a Cavalier inherited one copy of the variant SOD1 gene  tested? 
This result will not impact a Cavalier King Charles Spaniels Health.

What does the result mean if a Cavalier inherited both copies of the variant SOD1 gene  tested?
Research indicates that this genetic variant will not increase the risk that Cavalier King Charles Spaniels will develop this condition.
​
Scientific Basis 
Cavalier King Charles Spaniels have been included in research studies or have had follow-up by our experts that indicate that this genetic variant will not increase the risk of Cavalier King Charles Spaniels developing clinical disease. It is possible that the genetic background that predominates in some breeds prevents the development of symptoms even in dogs testing affected (at risk).



Karen Dennehy & Natalija Zeljic
Small World Puppies (Taurunum Angels Kennel)